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Daniel R Karlin

4 papers in the library · 23 citations · publishing 2023-2026

Papers

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720. Unraveling anxiolytic and anti-addictive properties of lysergic acid diethylamide in a model of alcohol use disorder

International Journal of Neuropsychopharmacology September 9, 2026 T Solomon, R Barrow, D Karlin et al.

Abstract Background Effective and well-tolerated pharmacotherapies for generalized anxiety disorder (GAD), which is one of the most common psychiatric disorders, are needed. Aims & Objectives To determine the dose-response relationship of MM120 (lysergide D-tartrate) in adults with moderate to severe GAD. Method This phase 2b, multicenter, randomized, double-blind, placebo-controlled study...

Single Treatment With MM120 (Lysergide) in Generalized Anxiety Disorder: A Randomized Clinical Trial.

JAMA October 21, 2025 Reid Robison, Robert Barrow, Craig Conant et al. 22 citations

Effective and well-tolerated pharmacotherapies for generalized anxiety disorder (GAD), which is one of the most common psychiatric disorders, are needed. To determine the dose-response relationship of MM120 (lysergide D-tartrate) in adults with moderate to severe GAD. This phase 2b, multicenter, randomized, double-blind, placebo-controlled study enrolled 198 adults aged 18 to 74 years with a...

Updates in palliative care of gynecologic oncology patients.

Current opinion in obstetrics & gynecology February 1, 2025 Teresa Khoo, Daniel R Karlin, Christopher Pietras

This review assesses the impact of early integration of palliative care and the disparities that exist among patients with gynecologic malignancies. It also highlights the recent advances in symptom management, goals of care communication, and end of life care. Although palliative care has been utilized earlier, there are still barriers to its integration both nationally and worldwide,...

Evaluating passive physiological data collection during Spravato treatment.

Frontiers in digital health 2023 Todd M Solomon, Matus Hajduk, Martin Majernik et al. 1 citation

Spravato and other drugs with consciousness-altering effects show significant promise for treating various mental health disorders. However, the effects of these treatments necessitate a substantial degree of patient monitoring which can be burdensome to healthcare providers and may make these treatments less accessible for prospective patients. Continuous passive monitoring via digital devices...