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Abdelrahman Sharafeldin

3 papers in the library · 102 citations · publishing 2023-2025

Papers

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Adversarial testing of global neuronal workspace and integrated information theories of consciousness.

Nature June 1, 2025 Oscar Ferrante, Urszula Gorska-Klimowska, Simon Henin et al. 94 citations

Different theories explain how subjective experience arises from brain activity1,2. These theories have independently accrued evidence, but have not been directly compared3. Here we present an open science adversarial collaboration directly juxtaposing integrated information theory (IIT)4,5 and global neuronal workspace theory (GNWT)6-10 via a theory-neutral consortium11-13. The theory...

Slow and fast cortical cholinergic arousal is reduced in a mouse model of focal seizures with impaired consciousness.

Cell Reports December 24, 2024 Lim-Anna Sieu, Shobhit Singla, Jiayang Liu et al. 8 citations

Patients with focal temporal lobe seizures often experience loss of consciousness associated with cortical slow waves, like those in deep sleep. Previous work in rat models suggests that decreased subcortical arousal causes depressed cortical function during focal seizures. However, these studies were performed under light anesthesia, making it impossible to correlate conscious behavior with...

An adversarial collaboration to critically evaluate theories of consciousness

bioRxiv Preprint Server June 23, 2023 Oscar Ferrante, Urszula Gorska-Klimowska, Simon Henin et al. preprint

Different theories explain how subjective experience arises from brain activity1,2. These theories have independently accrued evidence, yet, confirmation bias and dependence on design choices hamper progress in the field3. Here, we present an open science adversarial collaboration which directly juxtaposes Integrated Information Theory (IIT)4,5 and Global Neuronal Workspace Theory (GNWT)6–10,...