Pharmacological characterization of cannabidiol as a negative allosteric modulator of the 5-HT2A receptor.
Cellular signalling March 1, 2025 Etienne Billard, Alexandre Torbey, Antonio Inserra et al. 10 citations
Promising clinical evidence suggests that psychedelic compounds, like lysergic acid diethylamide (LSD), have therapeutic value for treatment of psychiatric disorders. However, they often produce hallucinations and dissociative states, likely mediated by the serotonin (5-HT) receptor 5-HT2A, raising challenges regarding therapeutic scalability. Given the reported antipsychotic effects of...
DOI: 10.1016/j.cellsig.2025.111588 (opens in new tab)
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Entheogens
Psychedelic drugs
Neuroscience brain science
Neural research
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