Psychopharmacology Bulletin
August 12, 2025
Dustin Latimer, Michael D. Stocker, Kia Sayers et al.
10 citations
Post-traumatic stress disorder (PTSD) has become one of the most common psychiatric diagnosis in the United States specifically within the veteran population. The current treatment options for this debilitating diagnosis include trauma-focused psychotherapies along with selective serotonin reuptake inhibitors (SSRI) and serotonin-norepinephrine reuptake inhibitors (SNRI). 1 MDMA has recently...
Psychopharmacology Bulletin
August 12, 2025
Priyanka Ghosh, Omar Viswanath
1 citation
We read a recent article published by CNN titled “Ketamine offers lifeline for people with severe depression, suicidal thoughts1” with great interest. The article traces the story of a man with a 35-year history of severe refractory depression, suicidal ideation, and recent suicide attempts who was successfully treated with ketamine as a last resort after failing dozens of other pharmacologic...
Current Pain and Headache Reports
June 19, 2025
Elika D Javaheri, Christopher Wie, Stephen Covington et al.
3 citations
As higher doses of ketamine are being used in numerous medical conditions such as Complex Regional Pain Syndrome (CRPS), it is critical to examine common adverse effects (AEs) explicitly associated with high doses of ketamine (HDK). HDK is often associated with psychiatric symptoms such as agitation, anxiety, and sleep disturbances. Psychiatric effects have been documented in various methods of...
Current Pain and Headache Reports
January 14, 2025
Alan D. Kaye, Brynne E Tynes, Coplen D Johnson et al.
6 citations
Complex Regional Pain Syndrome (CRPS) is a neuropathic pain disorder characterized by pain disproportionate to the inciting event that is constant for an extended duration. Numerous treatment options for this condition have been explored with unsatisfactory results in many cases. Ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist typically used as an anesthetic and analgesic, presents...
Current Pain and Headache Reports
January 7, 2025
Natalie H Strand, Madeline Whitney, Brooks Johnson et al.
9 citations
Chronic pain affects approximately 1.5 billion people worldwide, representing the leading cause of disability and a significant financial burden on healthcare systems. Conventional treatments, such as opioids and non-steroidal anti-inflammatory drugs, are frequently linked to adverse effects, including dependency and gastrointestinal issues, and often offer limited long-term relief. This review...
Annals of medicine
December 1, 2024
Alaa Abd-Elsayed, Cain W Stark, Natasha Topoluk et al.
41 citations
Complex regional pain syndrome (CRPS) is a debilitating chronic pain condition that, although exceedingly rare, carries a significant burden for the affected patient population. The complex and ambiguous pathophysiology of this condition further complicates clinical management and therapeutic interventions. Furthermore, being a diagnosis of exclusion requires a diligent workup to ensure an...