Javier Jareño Redondo

2 papers in the library · 29 citations · publishing 2024-2025

Papers

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Examining the pharmacokinetic and pharmacodynamic interaction of N,N-dimethyltryptamine and harmine in healthy volunteers: Α factorial dose-escalation study.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie March 1, 2025 Klemens Egger, Javier Jareño Redondo, Jovin Müller et al. 14 citations

Ayahuasca, a traditional psychoactive Amazonian brew, usually contains N,N-dimethyltryptamine (DMT) and β-carboline (harmine, harmaline, tetrahydroharmine) monoamine oxidase inhibitors. However, the pharmacological interactions between these compounds remain incompletely understood. In this study, we developed an ayahuasca-inspired formulation containing DMT and harmine, aiming to...

DOI: 10.1016/j.biopha.2025.117908 Full text DMT Ayahuasca pharmahuasca Harmine Pharmacokinetics +5

Meditating on psychedelics. A randomized placebo-controlled study of DMT and harmine in a mindfulness retreat

Journal of Psychopharmacology September 27, 2024 Daniel Meling, Klemens Egger, Jovin Mueller et al. 15 citations

Background: In recent years, both meditation and psychedelics have attracted rapidly increasing scientific interest. While the current state of evidence suggests the promising potential of psychedelics, such as psilocybin, to enhance meditative training, it remains equivocal whether these effects are specifically bound to psilocybin or if other classical psychedelics might show synergistic...

DOI: 10.1177/02698811241282637 Ayahuasca Meditation Mindfulness Psilocybin +4