Emerging Medications for Treatment-Resistant Depression: A Review with Perspective on Mechanisms and Challenges
Brain Sciences February 6, 2025 Michael J Lucido, Boadie W Dunlop 15 citations
Background/Objectives: Non-response to initial treatment options for major depressive disorder (MDD) is a common clinical challenge with profound deleterious impacts for affected patients. Few treatments have received regulatory approval for treatment-resistant depression (TRD). Methods: A systematic search of United States and European Union clinical trials registries was conducted to identify...