Acute psilocybin and ketanserin effects on cerebral blood flow: 5-HT2AR neuromodulation in healthy humans.
Journal of Cerebral Blood Flow & Metabolism February 26, 2025 Kristian Larsen, Ulrich Lindberg, Brice Ozenne et al. 9 citations
Psilocin, the active metabolite of psilocybin, is a psychedelic and agonist at the serotonin 2A receptor (5-HT2AR) that has shown positive therapeutic effects for brain disorders such as depression. To elucidate the brain effects of psilocybin, we directly compared the acute effects of 5-HT2AR agonist (psilocybin) and antagonist (ketanserin) on cerebral blood flow (CBF) using pseudo-continuous...
DOI: 10.1177/0271678x251323364 (opens in new tab)
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Psilocybin
Psychedelics hallucinogens
Entheogens
Psychedelic drugs
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