2 papers in the library · 49 citations · publishing 1978-1979
Southern medical journal October 1979 J R Smythies
This paper reviews the present status of the transmethylation and the dopamine hypotheses of schizophrenia and presents recent data on the definitive identification and measurement of the endogenous hallucinogen, dimethyltryptamine (DMT) in human cerebrospinal fluid and urine. Elevated levels are found in some cases of schizophrenia and of liver disease. Evidence is discussed showing that DMT...
The British Journal of Psychiatry February 1, 1978 L Corbett, S T Christian, R D Morin et al. 49 citations
The incidence and quantities of dimethyltryptamine and O-methylbufotenine were studied in the cerebrospinal fluid of patients suffering acute schizophrenic illnesses and in surgical and neurological control groups. Some schizophrenic patients have higher levels of both amines than do controls, though the differences in distribution did not reach statistical significance in the sample studied....