Classic Psychedelics for the Treatment of Depression: Potential Benefits and Challenges.
Drugs May 1, 2025 Sharmin Ghaznavi, Sarah G Richter 6 citations
There has been a recent resurgence in research on psychedelics as therapeutic agents for psychiatric conditions. This leading article outlines the studies to date of classic psychedelic treatments for treatment-resistant depression and major depression, including psilocybin, ayahuasca, dimethyltryptamine (DMT), and O-methyl-bufotenine (5-Me-O DMT). We discuss the potential of expanding...
DOI: 10.1007/s40265-025-02172-2 (opens in new tab)
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Mental health
Depression treatment
Clinical research
Therapeutic breakthroughs
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