Responses of the extrapyramidal and limbic substance P systems to ibogaine and cocaine treatments.
European Journal of Pharmacology February 25, 2000 M E Alburges, B P Ramos, L Bush et al. 21 citations
Ibogaine is an indolamine found in the West Africa shrub, Tabernanthe iboga, and has been proposed for the treatment of addiction to central nervous system (CNS) stimulants such as cocaine and amphetamine. The mechanism of ibogaine action and its suitability as a treatment for drug addiction still remains unclear. Since previous studies demonstrated differential effects of stimulants of abuse...