Iboga compounds reverse the behavioural disinhibiting and corticosterone effects of acute methamphetamine: Implications for their antiaddictive properties.
Pharmacology, Biochemistry, and Behavior 2001 Karen K. Szumlinski, R E Haskew, M Y Balogun et al. 28 citations
This study investigated the effects of pretreatment with the putative antiaddictive compound, ibogaine (IBO), and its synthetic derivative, 18-methoxycoronaridine (18-MC), on the changes in behaviour in an elevated plus maze and the changes in corticosterone (CORT) produced by a low dose of methamphetamine (METH). In the elevated plus maze, the acute administration of METH (0.1 mg/kg ip, -20...
DOI: 10.1016/s0091-3057(01)00564-0 (opens in new tab)
Full text (opens in new tab)
Iboga compounds
Ibogaine derivatives
Iboga alkaloids
Stimulant addiction treatment
+11