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Shepard Siegel

1 paper in the library · 17 citations · publishing 2002

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Ibogaine interferes with motivational and somatic effects of naloxone-precipitated withdrawal from acutely administered morphine.

Progress in neuro-psychopharmacology & biological psychiatry February 1, 2002 Linda A Parke, Page Burton, Robert V Mcdonald et al. 17 citations

It has been reported that ibogaine interferes with somatic withdrawal reactions in rats chronically treated with morphine. The present experiments demonstrated that ibogaine also interferes with motivational withdrawal reactions and somatic withdrawal reactions in rats treated with morphine on only two occasions. On each of two conditioning trials, naloxone was administered 24 h following an...