The hallucinogen 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is structurally similar to other indoleamine hallucinogens such as LSD. The present study examined the effects of 5-MeO-DMT in rats using the Behavioral Pattern Monitor (BPM), which enables analyses of patterns of locomotor activity and exploration, and the prepulse inhibition of startle (PPI) paradigm. A series of interaction...
Since being classified as a Schedule I controlled substance, MDMA (3,4-methylenedioxy-N-methylamphetamine; "ecstasy") has been the subject of controversy regarding its potential therapeutic usage, increased use by young people in the "Rave" culture, and issues of potential neurotoxicity. This review article summarizes much of the animal and human studies of the general behavioral effects of...