Jenelle K Bray

The structure of human serotonin 2c G-protein-coupled receptor bound to agonists and antagonists.

Journal of molecular graphics & modelling August 1, 2008 Jenelle K Bray, William A Goddard 35 citations

We used the MembStruk computational procedure to predict the three-dimensional (3D) structure for the serotonin 5-HT(2C) G-protein-coupled receptor (GPCR). Using this structure, we used the MSCDock computational procedure to predict the 3D structures for bound ligand-protein complexes for agonists such as serotonin and antagonists such as ritanserin, metergoline, and methiothepin. In addition,...