L Saso

Ibogaine reduces organ colonization in murine systemic and gastrointestinal Candida albicans infections.

Journal of medical microbiology July 1, 2005 M Yordanov, P Dimitrova, S Patkar et al. 19 citations

In the present study the effect of the indole alkaloid ibogaine on the in vitro lipolytic activity and adherence to epithelial cells of Candida albicans was investigated. The substance was administered intraperitoneally at a dose of 5 mg kg(-1) day(-1) in mice with disseminated and gastrointestinal C. albicans infections. Ibogaine significantly decreased the rate of mortality and the number of...