Depression is a highly prevalent mental disorder worldwide, and its cognitive rigidity-characterized by persistent negative beliefs resistant to countervailing evidence-remains a critical puzzle in philosophical psychiatry and clinical psychology. Existing theories of abductive reasoning have struggled to explain why similar adversities lead to rigid negative cognition in some individuals but...
The stems of Ervatamia yunnanensis have afforded a new indole alkaloid, ervataine (1), whose structure was determined by spectroscopic analysis. Five known compounds, ibogaine (2) coronaridine (3), heyneanine (4), voacangine hydroxyindolenine (5) and coronaridine hydroxyindolenine (6), were also isolated.