Three-dimensional reconstructions of zebrafish swimming paths (Cachat et al. 2011) are a new technique to discover novel, meaningful behavioral patterns evoked by different experimental manipulations. Compared to traditional 2D traces, 3D swim path reconstructions enable both macro-level (general) and micro-level (specific/repeated) analyses of potentially meaningful behavioral patterns,...
An indole alkaloid, ibogaine is the principal psychoactive component of the iboga plant, used by indigenous peoples in West Africa for centuries. Modulating multiple neurotransmitter systems, the drug is a potent hallucinogen in humans, although its psychotropic effects remain poorly understood. Expanding the range of model species is an important strategy for translational neuroscience...