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Niels Bjerre Holm

2 papers in the library · 17 citations · publishing 2017-2018

Papers

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Bromo-dragonfly, a psychoactive benzodifuran, is resistant to hepatic metabolism and potently inhibits monoamine oxidase A.

Toxicology Letters October 1, 2018 Carolina Noble, Niels Bjerre Holm, Marie Mardal et al. 17 citations

Bromo-dragonfly is a benzodifuran derivative known as one of the most potent 5-HT2A-receptor agonists within this chemical class, with long-lasting effects of up to 2-3 days. In addition to hallucinogenic effects, the drug is a potent vasoconstrictor, resulting in severe adverse effects, such as necrosis of the limbs. In some cases, intoxication has had fatal outcomes. Little is known about the...

DOI: 10.1016/j.toxlet.2018.07.018 (opens in new tab) Full text (opens in new tab) Benzodifuran High-resolution mass spectrometry Inhibition Metabolism +2

Characterization of the hepatic cytochrome P450 enzymes involved in the metabolism of 25I-NBOMe and 25I-NBOH.

Drug Testing and Analysis May 1, 2017 Line Marie Nielsen, Niels Bjerre Holm, Sebastian Leth-Petersen et al.

The dimethoxyphenyl-N-((2-methoxyphenyl)methyl)ethanamine (NBOMe) compounds are potent serotonin 5-HT2A receptor agonists and have recently been subject to recreational use due to their hallucinogenic effects. Use of NBOMe compounds has been known since 2011, and several non-fatal and fatal intoxication cases have been reported in the scientific literature. The aim of this study was to...