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Jessika Urbanavicius

2 papers in the library · 45 citations · publishing 2020

Papers

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A Single Administration of the Atypical Psychedelic Ibogaine or Its Metabolite Noribogaine Induces an Antidepressant-Like Effect in Rats.

ACS Chemical Neuroscience June 3, 2020 Paola Rodrı Guez, Jessika Urbanavicius, José Pedro Prieto et al. 44 citations

Anecdotal reports and open-label case studies in humans indicated that the psychedelic alkaloid ibogaine exerts profound antiaddictive effects. Ample preclinical evidence demonstrated the efficacy of ibogaine, and its main metabolite, noribogaine, in substance-use-disorder rodent models. In contrast to addiction research, depression-relevant effects of ibogaine or noribogaine in rodents have...

DOI: 10.1021/acschemneuro.0c00152 (opens in new tab) Full text (opens in new tab) Depression Serotonin Sert Preclinical test +4

A Single Administration of the Atypical Psychedelic Ibogaine or its Metabolite Noribogaine Induces an Antidepressant-like Effect in Rats

ChemRxiv March 19, 2020 Paola Rodrı́guez, Jessika Urbanavicius, José Pedro Prieto et al. 1 citation preprint

Anecdotal reports and open label case studies in humans indicated that the psychedelic alkaloid ibogaine exert profound anti-addictive effects. Ample preclinical evidence demonstrated the efficacy of ibogaine, and its main metabolite noribogaine, in substance use disorder rodent models. In contrast to addiction research, depression-relevant effects of ibogaine or noribogaine in rodents have not...

DOI: 10.26434/chemrxiv.12001407 (opens in new tab) Pharmacology Antidepressant Behavioural despair test Metabolite +1