In Vitro Psilocybin Synthesis by Co‐Immobilized Enzymes
Chemistry - A European Journal April 9, 2025 Tim Schäfer, Thomas Krüger, Jakob Worbs et al. 2 citations
Abstract Advanced clinical trials investigate the Psilocybe magic mushroom natural product psilocybin as a treatment against major depressive disorder. Currently, synthetic material is used to meet the demand for legitimate pharmaceutical purposes. Here, we report an in vitro approach to biocatalytically produce psilocybin on a solid‐phase matrix charged with five covalently bound biosynthetic...
DOI: 10.1002/chem.202501037 (opens in new tab)
Psilocybin
Enzyme
Biochemistry
Tryptamine
+4