Rob Ter Heine

The pharmacokinetics and pharmacodynamics of ibogaine in opioid use disorder patients.

Journal of Psychopharmacology May 1, 2024 Thomas Knuijver, Rob Ter Heine, Arnt Schellekens et al. 15 citations

Ibogaine is a hallucinogenic drug that may be used to treat opioid use disorder (OUD). The relationships between pharmacokinetics (PKs) of ibogaine and its metabolites and their clinical effects on side effects and opioid withdrawal severity are unknown. We aimed to study these relationships in patients with OUD undergoing detoxification supported by ibogaine. The study was performed in 14...