Mindfulness-Based Stress Reduction adapted to pregnant women with psychosocial vulnerabilities - a randomized feasibility trial in a Danish hospital-based outpatient setting.
Pilot and Feasibility Studies June 21, 2025 Sine Skovbjerg, Michelle Kolls, Anette Kjærbye-Thygesen et al.
A feasibility trial of prenatal mindfulness-based stress reduction (MBSR) for pregnant women with psychosocial vulnerabilities found the intervention feasible in a clinical setting, supporting a future randomized controlled trial. Of 123 eligible women, 73 (59.3%) consented; 37 were assigned to MBSR and 36 to a waitlist. Only 54.1% of the intervention group completed the program, and loss to follow-up was high (56.8% intervention, 50% control). Secondary outcomes—mental well-being, perceived stress, anxiety, depression, decentering, mindfulness, and self-compassion—trended in expected directions except for reflective functioning. Strategies to improve adherence and reduce missing data are recommended.