Qian Wang

2 papers in the library · publishing 2023-2026

Papers

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Investigation of Esketamine Administration During Surgical Procedures for the Alleviation of Postoperative Anxiety and Depression in Adolescent Patients: A Randomized Controlled Trial.

Drug Design, Development and Therapy 2026 Yanhong Li, Kuangyu Zhao, Peipei Cao et al.

Surgical stress can lead to postoperative anxiety and depression, especially in adolescents. These complications reduce quality of life and increase medical burdens, but perioperative psychological interventions for adolescents are limited, and related mechanisms remain unclear. Esketamine (S-ketamine), an N-methyl-D-aspartate receptor (NMDAR) antagonist, has analgesic, sedative,...

DOI: 10.2147/dddt.s587626 Full text S-ketamine Inflammatory markers Postoperative pain

Mapping metabolite change in the mouse brain after esketamine injection by ambient mass spectrometry imaging and metabolomics.

Frontiers in Psychiatry May 10, 2023 Guan-Xi Liu, Ze-Lin Li, Su-Yan Lin et al.

Ketamine is a new, fast, and effective antidepression treatment method; however, the possible dissociation effects, sensory changes, abuse risk, and the inability to accurately identify whether patients have a significant response to ketamine limit its clinical use. Further exploration of the antidepressant mechanisms of ketamine will contribute to its safe and practical application....

DOI: 10.3389/fpsyt.2023.1109344 Full text Depression Ketamine Antidepressant Mass spectrometry imaging +1