Mapping metabolite change in the mouse brain after esketamine injection by ambient mass spectrometry imaging and metabolomics.
Frontiers in Psychiatry May 10, 2023 Guan-Xi Liu, Ze-Lin Li, Su-Yan Lin et al.
Ketamine is a new, fast, and effective antidepression treatment method; however, the possible dissociation effects, sensory changes, abuse risk, and the inability to accurately identify whether patients have a significant response to ketamine limit its clinical use. Further exploration of the antidepressant mechanisms of ketamine will contribute to its safe and practical application....
DOI: 10.3389/fpsyt.2023.1109344 (opens in new tab)
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Depression
Ketamine
Antidepressant
Mass spectrometry imaging
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