Effects of Intranasal dexmedetomidine and esketamine for premedication on postoperative pain after tonsillectomy and adenoidectomy in children: a randomized clinical trial.
BMC Anesthesiology July 1, 2025 Jun-Wei Qi, Chuang Li, Xin-Yuan Qiu et al. 2 citations
Postoperative acute pain is a common issue in children after surgery. Our study aimed to investigate whether preoperative use of a dexmedetomidine-esketamine combination could reduce postoperative pain in children undergoing tonsillectomy and adenoidectomy and reduce side effects, such as bradycardia, hypotension or emergence delirium. In this double-blind, randomised controlled clinical trial,...