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Andrew J Barnhart

2 papers in the library · 17 citations · publishing 2023-2025

Papers

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Consciousness and Human Brain Organoids: A Conceptual Mapping of Ethical and Philosophical Literature.

AJOB Neuroscience July 9, 2025 Aileen Van Gyseghem, Kris Dierickx, Andrew J Barnhart 17 citations

Human brain organoids (HBOs) are three-dimensional structures derived from human pluripotent stem cells that model aspects of fetal brain development. As HBO models grow more complex, ethical concerns arise, particularly around the potential for consciousness. Defining and detecting consciousness in HBOs remains unresolved, with existing theories offering conflicting predictions. This...

DOI: 10.1080/21507740.2025.2519459 (opens in new tab) Full text (opens in new tab) Human brain organoids Lab-grown brain models Organoid intelligence Bioethics +7

Ethical, legal and social aspects of human cerebral organoids and their governance in Germany, the United Kingdom and the United States.

Frontiers in Cell and Developmental Biology 2023 Anja Pichl, Robert Ranisch, Ozan Altan Altinok et al.

Human cerebral organoids (HCOs) are model systems that enable researchers to investigate the human brain in ways that had previously been impossible. The emergence of HCOs was accompanied by both expert and layperson discussions concerning the possibility of these novel entities developing sentience or consciousness. Such concerns are reflected in deliberations about how to handle and regulate...