Fixed dose combination dextromethorphan-bupropion: A hope for treatment resistant depression (TRD).
Indian Journal of Psychiatry June 1, 2025 Ranjan Das, Rajarshi Chakravarty, Varaha V Gantait et al. 4 citations
Treatment resistant depression (TRD) has been identified as non-response to depression with adequate dose and trial of two antidepressant medications of different classes. Near about 30% depressive patients are TRD cases. Olanzapine-fluoxetine combination, rTMS, Intravenous ketamine and Electroconvulsive therapy have been till now studied in TRD. Dextromethorphan-bupropion is a newer...