Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system
bioRxiv Preprint Server April 12, 2023 Malika S. Datta, Yannan Chen, Shradha Chauhan et al. 6 citations preprint
Ketamine is a multifunctional drug with clinical applications as an anesthetic, as a pain management medication and as a transformative fast-acting antidepressant. It is also abused as a recreational drug due to its dissociative property. Recent studies in rodents are revealing the neuronal mechanisms that mediate the complex actions of ketamine, however, its long-term impact due to prolonged...