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John Beggs

3 papers in the library · 15 citations · publishing 2020-2024

Papers

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The serotonergic psychedelic N,N-dipropyltryptamine alters information-processing dynamics in cortical neural circuits

arXiv Preprint Archive October 31, 2023 Thomas F. Varley, Daniel Havert, Leandro Fosque et al.

Most of the recent work in psychedelic neuroscience has been done using non-invasive neuroimaging, with data recorded from the brains of adult volunteers under the influence of a variety of drugs. While this data provides holistic insights into the effects of psychedelics on whole-brain dynamics, the effects of psychedelics on the meso-scale dynamics of cortical circuits remains much less...

Differential Effects of Propofol and Ketamine on Critical Brain Dynamics

bioRxiv Preprint Server March 27, 2020 Thomas F. Varley, Olaf Sporns, Aina Puce et al. 3 citations preprint

Whether the brain operates at a critical ‘‘tipping” point is a long standing scientific question, with evidence from both cellular and systems-scale studies suggesting that the brain does sit in, or near, a critical regime. Neuroimaging studies of humans in altered states of consciousness have prompted the suggestion that maintenance of critical dynamics is necessary for the emergence of...