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Colleen Hanlon

3 papers in the library · 36 citations · publishing 2016-2022

Papers

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Evidence for altered neural activity patterns after MDMA-assisted therapy in adults with chronic and severe post-traumatic stress disorder: a pilot study

medRxiv May 27, 2022 S. P. Singleton, J. B. Wang, M. Mithoefer et al. preprint

3,4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) for post-traumatic stress disorder (PTSD) has demonstrated promise in multiple clinical trials. MDMA is hypothesized to facilitate the therapeutic process, in part, by decreasing fear response during fear memory processing while increasing extinction learning retention. The acute administration of MDMA in healthy controls modifies...

Altered brain activity and functional connectivity after MDMA-assisted therapy for post-traumatic stress disorder.

Frontiers in Psychiatry 2022 S Parker Singleton, Julie B. Wang, Michael C Mithoefer et al. 36 citations

3,4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) for post-traumatic stress disorder (PTSD) has demonstrated promise in multiple clinical trials. MDMA is hypothesized to facilitate the therapeutic process, in part, by decreasing fear response during fear memory processing while increasing extinction learning. The acute administration of MDMA in healthy controls modifies recruitment...

Abnormal medial prefrontal cortex activity in heavy cannabis users during conscious emotional evaluation.

Psychopharmacology March 1, 2016 Michael J Wesley, Joshua A Lile, Colleen Hanlon et al.

Long-term heavy cannabis users (cannabis users) who are not acutely intoxicated have diminished subconscious neural responsiveness to affective stimuli. This study sought to determine if abnormal processing extends to the conscious evaluation of emotional stimuli. Functional magnetic resonance imaging (fMRI) was used to examine brain activity as cannabis users (N = 16) and non-cannabis-using...