General Hospital Psychiatry
December 9, 2025
Gerasimos Konstantinou, Joshua D. Rosenblat, Sarah Hales et al.
4 citations
The global demographic shift toward aging populations has intensified the need for innovative therapeutic interventions targeting late-life mental health conditions, notably depression, loneliness, and existential distress. Traditional pharmacological treatments often exhibit limited efficacy and poor tolerability in older patients, primarily due to age-related physiological changes and the...
Pilot and Feasibility Studies
October 28, 2025
Candice Richardson, Cindy Chan, Emily Macgregor et al.
1 citation
BACKGROUND: Individuals with advanced cancer often experience high levels of distress for which there are few standardized treatment approaches. Our multidisciplinary team has combined existing evidence-based approaches into Psilocybin-assisted Existential, Attachment, and RelationaL (PEARL) therapy. PEARL therapy combines elements from psilocybin-assisted psychotherapy, including preparatory...
Omega
July 10, 2025
Daniel Rosenbaum, Celina Carter, Brandon A Cirella et al.
1 citation
Background: There is promising evidence that psychedelic-assisted psychotherapy may be a powerful new treatment approach for mortality-related distress. However, less is known about the possible benefits for people experiencing grief. Aim: To explore what is known about using psychedelics to attend to grief following death due to advanced illness. Design: This scoping review followed Arskey and...
Healthcare policy = Politiques de sante
May 1, 2023
Daniel Rosenbaum, Sarah Hales, Daniel Z. Buchman
5 citations
We agree with Kratina et al. (2023) that the problem of psychological suffering at the end of life deserves attention from a policy standpoint and that psychedelic therapies show promise in this clinical context. However, we argue the following in this rejoinder: (1) disproportionate attention to psychedelics may overstate the current evidence base, potentially diverting resources away from...
AJOB Neuroscience
April 3, 2023
Daniel Rosenbaum, Matthew Cho, Evan Schneider et al.
11 citations
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