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Iva Totomanova

3 papers in the library · 5 citations · publishing 2025-2026

Papers

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Psychedelics and women’s mental health: the effects of female sex hormones on psychedelics’ efficacy and tolerability

Molecular Psychiatry August 4, 2026 Kim P. C. Kuypers, Natasha L. Mason, Aurelie Carlier et al.

Women experience a disproportionate burden of affective and stress-related disorders, with symptom variability shaped by endocrine transitions across the menstrual cycle, pregnancy, postpartum, and menopause. Although psychedelic-assisted therapies are increasingly investigated for these conditions, hormonal state represents a largely unaccounted determinant of variability in exposure,...

Between enhancement and risk: A critical review of psychedelic microdosing

Current Opinion in Psychology August 6, 2025 Iva Totomanova, Eline Haijen, Petra P M Hurks et al. 5 citations

Microdosing psychedelics, the regular use of low doses of LSD or psilocybin, have attracted growing public and scientific interest. This review synthesizes findings from 57 human studies on psychological and physiological outcomes in clinical and non-clinical populations. Reported benefits include improved mood, enhanced cognition, social functioning, and mental health, although findings are...

Potential therapeutic effects of psychedelics in small doses: Is there a role for microdosing in psychiatry?

International review of neurobiology 2025 Iva Totomanova, Eline Haijen, Petra P M Hurks et al.

Clinical trials using full doses of psychedelics have provided preliminary evidence supporting their safety and efficacy in treating a variety of physical and psychological conditions. Anecdotal reports indicate that even very small amounts of these substances may provide therapeutic benefits, though robust clinical studies are still needed. This chapter reviews the current experimental studies...