Co-occurring posttraumatic stress disorder and alcohol use disorder (PTSD-AUD) are highly prevalent among U.S. Veterans and associated with greater symptom severity, functional impairment, and poorer outcomes than either disorder alone. Existing treatments demonstrate modest effectiveness, with persistent challenges in engagement, retention, and sustained improvement. To evaluate the...
Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) commonly co-occur and are associated with more severe symptomatology than either disorder alone, increased risk of suicide, and poorer response to existing treatments. A promising therapeutic intervention is the integration of 3,4-methylenedioxymethamphetamine (MDMA) and psychotherapy. The Food and Drug Administration (FDA)...