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Michael S Worden

2 papers in the library · 2 citations · publishing 2024-2026

Papers

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MDMA-Assisted Therapy for Veterans with Comorbid Posttraumatic Stress Disorder and Alcohol Use Disorder: Clinical Outcomes from the First Open-Label Pilot Trial.

Alcohol October 30, 2026 Erica Eaton, Christy Capone, Brian J Gully et al.

Co-occurring posttraumatic stress disorder and alcohol use disorder (PTSD-AUD) are highly prevalent among U.S. Veterans and associated with greater symptom severity, functional impairment, and poorer outcomes than either disorder alone. Existing treatments demonstrate modest effectiveness, with persistent challenges in engagement, retention, and sustained improvement. To evaluate the...

DOI: 10.1016/j.alcohol.2026.107464 (opens in new tab) Full text (opens in new tab) Alcohol use disorder Comorbidity MDMA-Assisted Therapy Posttraumatic stress disorder +1

Design and methodology of the first open-label trial of MDMA-assisted therapy for veterans with post-traumatic stress disorder and alcohol use disorder: Considerations for a randomized controlled trial.

Contemporary Clinical Trials Communications October 1, 2024 Erica Eaton, Christy Capone, Brian J Gully et al. 2 citations

Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) commonly co-occur and are associated with more severe symptomatology than either disorder alone, increased risk of suicide, and poorer response to existing treatments. A promising therapeutic intervention is the integration of 3,4-methylenedioxymethamphetamine (MDMA) and psychotherapy. The Food and Drug Administration (FDA)...