Charlotte E Farquhar

Sex, THC, and hormones: Effects on density and sensitivity of CB1 cannabinoid receptors in rats.

Drug and Alcohol Dependence January 1, 2019 Charlotte E Farquhar, Christopher S Breivogel, Thomas F Gamage et al.

The recent NIH mandate to consider sex as a biological variable in preclinical research has focused attention on delineation of sex differences in behavior. To investigate mechanisms underlying sex differences in Δ9-tetrahydrocannabinol (THC) effects, we examined the effects of sex and gonadal hormones on CB1 receptors in cerebellum, hippocampus, prefrontal cortex, and striatum. Adult...