µ- and κ-Opioid receptor activation in the dorsal periaqueductal grey matter differentially modulates panic-like behaviours induced by electrical and chemical stimulation of the inferior colliculus.
Brain Research December 5, 2014 André Twardowschy, Norberto Cysne Coimbra
It has been shown that electrical stimulation of the mesencephalic tectum (MT) provokes defensive responses in both humans and rodents. During an emotional aversive state, some convergent studies have also demonstrated the existence of a complex interaction between endogenous opioid peptide- and γ-aminobutyric acid (GABA)-containing connections during fear-induced responses. It has been...
DOI: 10.1016/j.brainres.2014.11.062 (opens in new tab)
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Periaqueductal gray
Neurons
Animals
Rats, wistar
+19