Clinical and neurophysiological effects of imagery rehearsal therapy and targeted memory reactivation in post-traumatic stress disorder
Research Square October 14, 2026 Océane Lüthi, Vincent Rochas, Audrey Theux et al. preprint
Abstract Post-traumatic stress disorder is frequently associated with post-traumatic nightmares, which may be related to cortical hyperarousal. Imagery Rehearsal Therapy is the first-line treatment for nightmares. Targeted Memory Reactivation, which reactivates specific memories during sleep to enhance memory consolidation, has been shown to enhance the effects of Imagery Rehearsal Therapy in...