Psilocybin enhances conditioned place preference learning in planarians.
Behavioural Pharmacology October 13, 2026 Bart A. Ellenbroek, Beth Naylor, Jiun Youn
Psilocybin has emerged as a promising therapeutic agent, with clinical benefits attributed to enhanced neuroplasticity rather than acute pharmacological effects. However, the fundamental mechanisms underlying these effects remain poorly understood. Using planarians as a model system, we investigated whether psilocybin enhances associative learning using a conditioned place preference paradigm....
DOI: 10.1097/fbp.0000000000000903 (opens in new tab)
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Neuroplasticity
Psilocybin
Serotonin
Conditioned place preference
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