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Rochellys Diaz-Heijtz

1 paper in the library · publishing 2009

Papers

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Effects of repeated treatment of phencyclidine on cognition and gene expression in C57BL/6 mice.

The International Journal of Neuropsychopharmacology March 2009 Simret Beraki, Rochellys Diaz-Heijtz, Fadao Tai et al.

A number of studies indicate that glutamatergic N-methyl-D-aspartate (NMDA) neurotransmission is disturbed in schizophrenia partly based on the findings that NMDA receptor antagonists such as phencyclidine (PCP) can reproduce a schizophrenia-like syndrome in both humans and rodents. This study investigated whether repeated administration of low doses of PCP can induce cognitive dysfunctions in...