Biosynthesis of Salvinorin A: Overexpression and Biochemical Characterization of Carboxy Methyltransferase from EST of Salvia divinorum Glands
Planta Medica March 1, 2009 LM Kutrzeba, JK Zjawiony, HJ Koo et al. 1 citation
Abuse of unregulated substances by young adults has been a great concern of the US and international community. The active component of Salvia divinorum , salvinorin A ( 1 ) has a potent affinity to kappa opioid receptor in CNS. We studied the biosynthesis of this diterpenoid through the isolation of RNA and construction of cDNA library. Sequencing of the genetic material resulted in building...