Perceived effectiveness, tolerability, and discontinuation of lemborexant in real-world use: Evidence from online patient reports.
Sleep Medicine September 16, 2026 Abanoub J Armanious, Alexandra R Dunn, Caitlin E Martin et al.
Lemborexant is a dual orexin receptor antagonist (DORA) approved for the clinical management of insomnia. Clinical trials indicate that lemborexant improves sleep onset latency and sleep maintenance, with mild somnolence as the most common side effect. However, there is limited real-world evidence characterizing patient experiences with lemborexant, including perceived benefits, side effects,...