Frontal–striatal–thalamic circuit dysfunction and inferential processing between internal representations and external events across the psychosis spectrum
Frontiers in Psychiatry September 29, 2026 Naoyuki Katagiri, Hiromi Tagata, Takashi Uchino et al.
Background In psychopathology, schizophrenia has been understood as a disorder characterized by disturbances in subjective consciousness. Subjective consciousness and its relationship to interactions between internal representations and external events have been discussed in phenomenology. Recent computational neuroscience conceptualizes the brain as an inferential system that minimizes...