NMDA receptor modulation by Esculetin: Investigating behavioral, biochemical and neurochemical effects in schizophrenic mice model.
Saudi Pharmaceutical Journal April 1, 2024 Iqra Khalid, Uzma Saleem, Bashir Ahmad et al. 11 citations
Schizophrenia, a global mental health disorder affecting approximately 1 % of the population, is characterized by neurotransmitter dysregulation, particularly dopamine, serotonin, and glutamate. Current antipsychotic therapies, despite their efficacy, are accompanied by adverse effects, which has motivated researchers to investigate more secure substitutes. This study examines the potential...
DOI: 10.1016/j.jsps.2024.101994 (opens in new tab)
Full text (opens in new tab)
Ketamine
Bdnf
Esculetin
Oxidative stress
+6