Crystal J Jicha

Safety of oral dronabinol during opioid withdrawal in humans.

Drug and Alcohol Dependence December 1, 2015 Crystal J Jicha, Michelle R Lofwall, Paul A Nuzzo et al.

Opioid dependence remains a significant public health problem worldwide with only three FDA-approved treatments, all targeting the mu-opioid receptor. Dronabinol, a cannabinoid (CB) 1 receptor agonist, is currently under investigation as a novel opioid withdrawal treatment. This study reports on safety outcomes of dronabinol among adults in opioid withdrawal. Twelve adults physically dependent...