Abstract Background Long-term use of cannabis has long been associated with changes in cognition, including memory and learning, particularly verbal learning in man. However, evidence regarding the neurobiological underpinnings of impairments in memory following long-term cannabis use has not been consistent. Furthermore, to our knowledge none of the studies published to date have specifically...
BMJ Open2016R. Patel, R. Wilson, R. Jackson et al.
Objective To investigate whether cannabis use is associated with increased risk of relapse, as indexed by number of hospital admissions, and whether antipsychotic treatment failure, as indexed by number of unique antipsychotics prescribed, may mediate this effect in a large data set of patients with first episode psychosis (FEP). Design Observational study with exploratory mediation analysis....