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Guy Barry

1 paper in the library · publishing 2018

Papers

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THC exposure of human iPSC neurons impacts genes associated with neuropsychiatric disorders.

Translational Psychiatry April 25, 2018 Boris Guennewig, Maina Bitar, Ifeanyi Obiorah et al.

There is a strong association between cannabis use and schizophrenia but the underlying cellular links are poorly understood. Neurons derived from human-induced pluripotent stem cells (hiPSCs) offer a platform for investigating both baseline and dynamic changes in human neural cells. Here, we exposed neurons derived from hiPSCs to Δ9-tetrahydrocannabinol (THC), and identified diagnosis-specific...