PLoS One2018Mónica R Fernández-Cabrera, Alejandro Higuera-Matas, Isabel Fernaud-Espinosa et al.
Derivatives from the Cannabis plant are the most commonly abused illegal substances in the world. The main psychoactive component found in the plant, Δ-9-tetrahydrocannabinol (THC), exerts its effects through the endocannabinoid system. Manipulations of this system affect some types of learning that seem to be dependent on dorsal striatum synaptic plasticity. Dendritic spines exhibit important...