3,4‐methylenedioxymethamphetamine increases excitability in the dentate gyrus: role of 5HT2A receptor‐inducedPGE2 signaling
Journal of Neurochemistry March 1, 2016 Stuart A. Collins, Courtney L Huff, Nicolas Chiaia et al.
Abstract: 3,4‐methylenedioxymethamphetamine (MDMA) is a widely abused psychostimulant, which causes release of serotonin in various forebrain regions. Recently, we reported thatMDMAincreases extracellular glutamate concentrations in the dentate gyrus, via activation of 5HT2A receptors. We examined the role of prostaglandin signaling in mediating the effects of 5HT2A receptor activation on the...