Liming Xie

Astrocytes activation contributes to the antidepressant-like effect of ketamine but not scopolamine.

Pharmacology, Biochemistry, and Behavior July 2018 Yun Wang, Liming Xie, Ce Gao et al.

Depression is a common, debilitating mood disorder, but currently available antidepressants have several major drawbacks. Both ketamine and scopolamine attract more and more attention due to their rapid and sustained antidepressant activities. However, the molecular and cellular mechanism that underlies the therapeutic action of ketamine and scopolamine still remain to be elucidated....