Yanzhu Pu

Exploring the multifaceted potential of (R)-ketamine beyond antidepressant applications.

Frontiers in Pharmacology 2024 Senbing Zhang, Yanzhu Pu, Jianning Liu et al. 12 citations

(R, S)- and (S)-ketamine have made significant progress in the treatment of treatment-resistant depression (TRD) and have become a research focus in recent years. However, they both have risks of psychomimetic effects, dissociative effects, and abuse liability, which limit their clinical use. Recent preclinical and clinical studies have shown that (R)-ketamine has a more efficient and lasting...